May peace and blessings be on all the Messengers of God. Prophet Muhammad is a direct descendant of Isma'il, the first son of Prophet Ibrahim(Abraham). Prophet Muhammad was born in Makkah as a fullfilment of the prayer of Abraham as explained in the following verses of the Holy Quran, a book of revelations from God to the Prophet.

002.124  And remember that Abraham was tried by his Lord with certain commands,
which he fulfilled: He said: "I will make thee an Imam to the Nations." He pleaded:
"And also (Imams) from my offspring!" He answered: "But My Promise is not within
the reach of evil-doers."

002.125  Remember We made the House a place of assembly for men and a place of
safety; and take ye the station of Abraham as a place of prayer; and We covenanted
with Abraham and Isma'il, that they should sanctify My House for those who
compass it round, or use it as a retreat, or bow, or prostrate themselves (therein in
prayer).

002.126  And remember Abraham said: "My Lord, make this a City of Peace, and
feed its people with fruits,-such of them as believe in God and the Last Day." He said:
"(Yea), and such as reject Faith,-for a while will I grant them their pleasure, but will
soon drive them to the torment of Fire,- an evil destination (indeed)!"

002.127  And remember Abraham and Isma'il raised the foundations of the House
(With this prayer): "Our Lord! Accept (this service) from us: For Thou art the All-
Hearing, the All-knowing.

002.128  "Our Lord! make of us Muslims, bowing to Thy (Will), and of our progeny a
people Muslim, bowing to Thy (will); and show us our place for the celebration of
(due) rites; and turn unto us (in Mercy); for Thou art the Oft-Returning, Most
Merciful.

002.129  "Our Lord! send amongst them an Apostle of their own, who shall rehearse
Thy Signs to them and instruct them in scripture and wisdom, and sanctify them: For
Thou art the Exalted in Might, the Wise."

002.130  And who turns away from the religion of Abraham but such as debase their
souls with folly? Him We chose and rendered pure in this world: And he will be in
the Hereafter in the ranks of the Righteous.

002.131  Behold! his Lord said to him: "Bow (thy will to Me):" He said: "I bow (my
will) to the Lord and Cherisher of the Universe."